Well, it happened again.
Just three weeks after a complete re-install of Railworks, I was editing the NSAND route and RW froze up. No SBHH, just stopped responding. I killed the process with task manager.
Then, then after rebooting RW, the route wont load. It gets through the loading screen, and freezes. SBHH error. So, I completely removed the route with the package manger and reinstalled the whole thing. Still wont load. This is the same problem I had with the C&O route.
I have no idea what is going on, but its time to take yet another long break from this program.