I keep my game online all the time. The only time things get changed are if you do a verify (which I almost never do) or if DTG does a update of some asset and that only affects that item. I have two clicks active in case I need to re-install my mods.
Buzz 39 and holding. "Some people find fault like there's a reward for it."- Zig Ziglar "If you can dream it you can do it."- Walt Disney